TdC 147: Anti-inflamatórios - 7 armadilhas!

Notas do episódio

https://www.tadeclinicagem.com.br/guia/ Confira a promoção especial para o plano anual do Guia TdC: Receba em casa o Card de Consulta Rápida no Plantão, com os temas: IOT, ACLS, ATB, ECG, trombólise e reposição eletrolítica. Receba em casa o porta-crachá (tirante para crachá) do TdC. Ganhe R$ 50 OFF (de 449 por 399,00) 7 primeiros dias inteiramente grátis Use o CUPOM: GUIADZERO 🚨 www.tadeclinicagem.com.br/guia - Conheça o Guia TdC com 7 dias grátis 🚨 Pedro e Fred discutem sobre os principais efeitos colaterais dos anti-inflamatórios (renal, cardíaco e gastrintestinal) e sobre o uso tópico dos anti-inflamatórios. Veja o vídeo do Resumo Visual de 8 minutos com os principais destaques do episódio de AINES: https://youtu.be/e7Yz6oG6KsM Referências: 1. Derry, Sheena, et al. "Topical NSAIDs for chronic musculoskeletal pain in adults." Cochrane Database of Systematic Reviews 4 (2016). 2. Derry, Sheena, et al. "Topical NSAIDs for acute musculoskeletal pain in adults." Cochrane database of systematic reviews 6 (2015). 3. Baker, Megan, and Mark A. Perazella. "NSAIDs in CKD: are they safe?." American Journal of Kidney Diseases 76.4 (2020): 546-557. 4. Sharma, Leena. "Osteoarthritis of the knee." New England Journal of Medicine 384.1 (2021): 51-59. 5. Klinge, Stephen A., and Gregory A. Sawyer. "Effectiveness and safety of topical versus oral nonsteroidal anti-inflammatory drugs: a comprehensive review." The Physician and sportsmedicine 41.2 (2013): 64-74. 6. Drożdżal, Sylwester, et al. "Kidney damage from nonsteroidal anti‐inflammatory drugs—Myth or truth? Review of selected literature." Pharmacology Research & Perspectives 9.4 (2021): e00817. 7. Nissen, Steven E., et al. "Cardiovascular safety of celecoxib, naproxen, or ibuprofen for arthritis." New England Journal of Medicine 375 (2016): 2519-2529. 8. Laine, L., et al. "Risk factors for NSAID‐associated upper GI clinical events in a long‐term prospective study of 34 701 arthritis patients." Alimentary pharmacology & therapeutics 32.10 (2010): 1240-1248. 9. Masclee, Gwen MC, et al. "Risk of upper gastrointestinal bleeding from different drug combinations." Gastroenterology 147.4 (2014): 784-792. 10. Henry, David, et al. "Variability in risk of gastrointestinal complications with individual non-steroidal anti-inflammatory drugs: results of a collaborative meta-analysis." Bmj 312.7046 (1996): 1563-1566. 11. Kelly, Judith P., et al. "Risk of aspirin-associated major upper-gastrointestinal bleeding with enteric-coated or buffered product." The Lancet 348.9039 (1996): 1413-1416. 12. Rodríguez, Luis A. García, and Laura Barreales Tolosa. "Risk of upper gastrointestinal complications among users of traditional NSAIDs and COXIBs in the general population." Gastroenterology 132.2 (2007): 498-506. 13. Lanza, Frank L., et al. "Guidelines for prevention of NSAID-related ulcer complications." Official journal of the American College of Gastroenterology| ACG 104.3 (2009): 728-738. 14. Desai, Jay C., et al. "Primary prevention of adverse gastroduodenal effects from short-term use of non-steroidal anti-inflammatory drugs by omeprazole 20 mg in healthy subjects: a randomized, double-blind, placebo-controlled study." Digestive diseases and sciences 53.8 (2008): 2059-2065. 15. Takeuchi, Ken, et al. "Prevalence and mechanism of nonsteroidal anti-inflammatory drug–induced clinical relapse in patients with inflammatory bowel disease." Clinical Gastroenterology and Hepatology 4.2 (2006): 196-202. 16. Chey, William D., et al. "ACG clinical guideline: treatment of Helicobacter pylori infection." Official journal of the American College of Gastroenterology| ACG 112.2 (2017): 212-239.