TdC 70: COVID-19 - Atualizações

Notas do episódio

https://www.tadeclinicagem.com.br/guia/ Confira a promoção especial para o plano anual do Guia TdC: Receba em casa o Card de Consulta Rápida no Plantão, com os temas: IOT, ACLS, ATB, ECG, trombólise e reposição eletrolítica. Receba em casa o porta-crachá (tirante para crachá) do TdC. Ganhe R$ 50 OFF (de 449 por 399,00) 7 primeiros dias inteiramente grátis Use o CUPOM: GUIADZERO Rapha, Kaue e Fred discutem as atualizações no tratamento, diagnóstico e quadro clínico da COVID-19. Dúvidas e comentários manda pra gente no @tadeclinicagem Ou tadeclinicagem@gmail.com Minutagem 04:00 Testes diagnósticos do COVID 04:20 PCR - swab 07:33 Quando fazer e como interpretar o resultado? 11:50 Sorologia 18:02 Teste antígeno 19:00 Tratamento do COVID 19:50 Hidroxicloroquina 24:00 Ivermectina e Anitta 26:05 Anticorpos monoclonais 27:26 Azitromicina e infecção bacteriana secundária 31:00 Ferritina / Procalcitonina 31:46 Outros cuidados do paciente ambulatorial - isolamento 34:30 Uso do PCR para sair do isolamento 36:35 Quem deve ser isolado - contactantes 38:20 Tratamento do internado: Dexametasona 43:40 Rendesivir 46:40 Anticoagulação 49:28 Imunomodulador e plasma convalescentes 50:06 Resumos das drogas do tratamento 50:33 Tratamento não farmacológico 54:30 VNI x VM 56:24 Sequelas pós-COVID 59:15 Síndrome pós UTI (PICS) 64:00 Parosmia 66:30 Salves 67:15 Resposta do desafio da semana anterior 68:08 Desafio da semana REFERÊNCIAS: 1- https://www.fda.gov/news-events/press-announcements/coronavirus-covid-19-update-fda-informs-public-about-possible-accuracy-concerns-abbott-id-now-point (Accessed on May 19, 2020). 2- DINNES, Jacqueline et al. Rapid, point‐of‐care antigen and molecular‐based tests for diagnosis of SARS‐CoV‐2 infection. Cochrane Database of Systematic Reviews, n. 8, 2020. 3- JOUNG, Julia et al. Detection of SARS-CoV-2 with SHERLOCK one-pot testing. New England Journal of Medicine, v. 383, n. 15, p. 1492-1494, 2020. 4- GUDBJARTSSON, Daniel F. et al. Humoral immune response to SARS-CoV-2 in Iceland. New England Journal of Medicine, v. 383, n. 18, p. 1724-1734, 2020. 5- HANSON, Kimberly E. et al. Infectious Diseases Society of America Guidelines on the Diagnosis of Coronavirus Disease 2019 (COVID-19): Serologic Testing. Clinical Infectious Diseases, 2020. 6-Tweeter Eric Feigl-Ding. 7- HANSON, Kimberly E. et al. Infectious Diseases Society of America guidelines on the diagnosis of COVID-19. Clinical Infectious Diseases, 2020. 8- WATSON, Jessica; WHITING, Penny F.; BRUSH, John E. Interpreting a covid-19 test result. Bmj, v. 369, 2020. 9- DEL RIO, Carlos; COLLINS, Lauren F.; MALANI, Preeti. Long-term health consequences of COVID-19. Jama, v. 324, n. 17, p. 1723-1724, 2020. 10- https://www.idsociety.org/covid-19-real-time-learning-network/disease-manifestations--complications/post-covid-syndrome/ 11- RECOVERY Collaborative Group, Horby P, Lim WS, et al. Dexamethasone in Hospitalized Patients with Covid-19 - Preliminary Report. N Engl J Med 2020. 12- Paranjpe I, Fuster V, Lala A, et al. Association of treatment dose anticoagulation with in-hospital survival among hospitalized patients with COVID-19. Journal of the American College of Cardiology. 2020. [In Press]. 13- Spyropoulos AC, Lipardi C, Xu J, et al. Modified IMPROVE VTE Risk score and elevated D-dimer identify a high venous thromboembolism risk in acutely ill medical population for extended thromboprophylaxis. TH Open. 2020;4(1):e59-e65. 14- Horby P, Mafham M, Linsell L, et al. Effect of hydroxychloroquine in hospitalized patients with COVID-19: preliminary results from a multi-centre, randomized, controlled trial. medRxiv. 2020;Preprint. 15- Cavalcanti AB, Zampieri FG, Rosa RG, et al. Hydroxychloroquine with or without azithromycin in mild-to-moderate COVID-19. N Engl J Med. 2020. 16- Furtado RHM, Berwanger O, Fonseca HA, et al. Azithromycin in addition to standard of care versus standard of care alone in the treatment of patients admitted to the hospital with severe COVID-19 in Brazil (COALITION II): a randomised clinical trial. Lancet. 2020. Mais referências