#19 - Por que o organismo aceita sentir dor para se tornar mais forte?

Notas do episódio

Neste episódio falamos sobre alguns mecanismos de dor, adaptação, inflamação e como isso tudo se relaciona com o nosso corpo ficando mais forte ou mais adaptado. Refs.: Bodine SC, Stitt TN, et al. Akt/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy in vivo. Nat Cell Biol. 2001 Nov;3(11):1014-9. doi: 10.1038/ncb1101-1014. PMID: 11715023. Booth FW, Roberts CK, Laye MJ. Lack of exercise is a major cause of chronic diseases. Compr Physiol. 2012 Apr;2(2):1143-211. doi: 10.1002/cphy.c110025. PMID: 23798298; PMCID: PMC4241367. Calabrese EJ, Mattson MP. Hormesis provides a generalized quantitative estimate of biological plasticity. J Cell Commun Signal. 2011 Mar;5(1):25-38. doi: 10.1007/s12079-011-0119-1. Epub 2011 Feb 25. PMID: 21484586; PMCID: PMC3058190. Hornberger TA, Esser KA. Mechanotransduction and the regulation of protein synthesis in skeletal muscle. Proc Nutr Soc. 2004 May;63(2):331-5. doi: 10.1079/PNS2004357. PMID: 15294051. Humphrey JD, Dufresne ER, Schwartz MA. Mechanotransduction and extracellular matrix homeostasis. Nat Rev Mol Cell Biol. 2014 Dec;15(12):802-12. doi: 10.1038/nrm3896. Epub 2014 Oct 22. PMID: 25355505; PMCID: PMC4513363. Ingber DE. Mechanobiology and diseases of mechanotransduction. Ann Med. 2003;35(8):564-77. doi: 10.1080/07853890310016333. PMID: 14708967. Lim C, Nunes EA, et al. An Evidence-Based Narrative Review of Mechanisms of Resistance Exercise-Induced Human Skeletal Muscle Hypertrophy. Med Sci Sports Exerc. 2022 Sep 1;54(9):1546-1559. doi: 10.1249/MSS.0000000000002929. Epub 2022 Apr 6. PMID: 35389932; PMCID: PMC9390238. Mattson MP. Hormesis defined. Ageing Res Rev. 2008 Jan;7(1):1-7. doi: 10.1016/j.arr.2007.08.007. Epub 2007 Dec 5. PMID: 18162444; PMCID: PMC2248601. Sterling P. What is Health? Allostasis and the Evolution of Human Design. MIT Press. 2020. Su C, Zhang Z, Liang B, Zhou S, Long X. Effects of blood flow restriction combined with high-load training on muscle strength and sports performance in athletes: a systematic review and meta-analysis. Front Physiol. 2025 Jul 2;16:1603568. doi: 10.3389/fphys.2025.1603568. PMID: 40671707; PMCID: PMC12263612. Tao R, Yang Y, Wilson M, Chang JR, Liu C, Sit CHP. Comparative effectiveness of physical activity interventions on cognitive functions in children and adolescents with Neurodevelopmental Disorders: a systematic review and network meta-analysis of randomized controlled trials. Int J Behav Nutr Phys Act. 2025 Jan 13;22(1):6. doi: 10.1186/s12966-024-01702-7. PMID: 39806448; PMCID: PMC11731537. Wohlann T, Warneke K, et al. Influence of 8-weeks of supervised static stretching or resistance training of pectoral major muscles on maximal strength, muscle thickness and range of motion. Eur J Appl Physiol. 2024 Jun;124(6):1885-1893. doi: 10.1007/s00421-023-05413-y. Epub 2024 Jan 19. PMID: 38240811; PMCID: PMC11129965. Zügel M, Maganaris CN, et al. Fascial tissue research in sports medicine: from molecules to tissue adaptation, injury and diagnostics: consensus statement. Br J Sports Med. 2018 Dec;52(23):1497. doi: 10.1136/bjsports-2018-099308. Epub 2018 Aug 2. PMID: 30072398; PMCID: PMC6241620. Se deseja marcar uma consulta, mande mensagem no email profbaeta@gmail.com ou entre no site www.lucabaeta.com.br ou ainda, se preferir, mande mensagem no instagram @profbaeta